Epipremnum harlequin, also known as Pothos harlequin, is a very white variety of the common Pothos plant. Here are some tips for its maintenance:

1. **Light:**
- Tolerant of low light, but prefers bright indirect light.
- Avoid direct exposure to sunlight, as this can burn the leaves.

2. **Watering:**
- Allow the top of the soil to dry between waterings.
- Water moderately, taking care not to let the water stagnate in the saucer.

3. **Humidity:**
- Tolerates medium to high humidity levels.
- You can increase humidity by spraying water around the plant or placing a tray of water nearby.

4. **Temperature:**
- Maintain a constant ambient temperature between 18°C ​​and 30°C.

5. **Fertilizer:**
- Fertilize every 4 to 6 weeks during the growing period (spring and summer).
- Use a balanced or specially formulated liquid fertilizer for houseplants.

6. **Soil:**
- Use a mixture of well-draining potting soil with cocopeat.
- Make sure the pot has drainage holes.

7. **Cleaning the leaves:**
- Wipe the leaves with a damp cloth to remove dust.

8. **Spread:**
- You can easily propagate Epipremnum harlequin by taking cuttings and rooting them in water.

9. **Size:**
- Prune the plant to maintain an attractive shape.
- Remove yellow or damaged leaves to encourage growth.

10. **Pest Management:**
- Inspect the plant regularly for the presence of pests.
- Treat pest problems as soon as they appear with appropriate methods.

By following these care tips, you should be able to keep an Epipremnum harlequin healthy and enjoy its colorful, attractive leaves.